Lennox-Gastaut Syndrome

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Lennox-Gastaut Syndrome (LGS) is a rare form of epilepsy that is characterized by multiple seizure types, cognitive deficits and spike-and-wave complexes on the EEG. Causes of LGS are varied- ‘structural’ causes include injury during birth, asphyxia, premature birth and infections of the brain. Other cases, where a definite cause cannot be found are called ‘cryptogenic’. Symptoms of LGS usually appear between the second and sixth year of life, and is associated with refractoriness to anti-epileptic drugs (meaning conventional drugs for epilepsy do not work in children with LGS). Complete recovery is unusual, but there are treatment options to decrease seizure frequency and improve quality of life.”

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